Abstract: The continuous high-speed exploitation in Henan oilfield for many years has resulted in serious sand production, formation deficit, too much casing pressure, worse wellbore conditions, serious casing damage, and more channeling wells outside the tube year by year. In view of the problem of channeling out of oil-water wells, the technology of channeling sealing agent with high-strength and low-density was studied and the density of channeling sealing agent was 1.28 g/cm³. The results show that the salinity of water sample has little effect on the initial setting time and breakthrough pressure gradient strength of the channeling sealer. The interface bonding strength between channeling sealer and steel body is high and the temperature resistance is excellent. The field application shows an obvious effect, and that the daily liquid output is 8.5 m³, the daily oil output is 1.2 t.