Abstract: In the middle and later stages of Shengli oilfield development, the production water cut gradually increased, and the production pressure difference and liquid recovery strength increased, leading to increased sand production in oil wells, and the problem of sand filter pipe being blocked in production became more serious. Therefore, using segmented gravel packing sand control technology in horizontal wells, the open hole is segmented through the outer packer and reverse gravel packing plan, the long horizontal section is divided into several small well sections by several times of segmented packing construction, which can greatly improve the effect of long open hole section gravel packing and compaction in horizontal wells, slow down or avoid sand control screen being blocked in the process of production, improve the level of long section of sand control effect and life in horizontal wells. Field application shows that the open hole segmented packing sand control technology in horizontal wells is mature and reliable, which can effectively improve the packing effect and safety of long horizontal section in horizontal wells, and is an effective technology to improve sand control quality of long horizontal section in horizontal wells.