Abstract: Development in Zhongyuan oilfield is very difficult due to the highly fractured structures and complex reservoirs. High salinity of formation water results in serious!scaling in wellbore and pipeline networks. The main scale forming material is discovered to be calcium sulfate through study on scale forming mechanism of produced water in a typical gathering station. Scale formation trend and degree can be determined by using the Skillman method. An ideal anti-scaling additive is selected based on field scale control experiment and the scale prevent rate is up to 80%.