Abstract: Laminar flow commonly existed in horizontal wells because of gravity difference and its type is effected by well inclined angle and turned complicated under the influence, which caused change in measurement instrument and parameter. The traditional decollement model is not applicable to production fluid profile interpretation in horizontal wells. This article analyzed the characteristic of oil and water two phase fluid horizontal wells and discussed the interpretation method of integrated measurement instruments oil and water two phase production fluid profile in Horizontal Wells and carried on case analysis to some well.