Abstract: The fracturing innovation is very difficult in Zhongyuan oilfield for its low permeability, high temperature, multiple fault blocks and complex formation conditions. Wen33 is a typical fault block with low permeability and very high pressure. Conventional fracturing formation can't be applied in in this block, otherwise sand injection can not be fully finished or sand out arised earlier or even some accidents such as working string stucked by sand will happen. To make a sucessful fracturing treatment, some corresponding strategies must be adopted. It increased the success ratio and efficiency by selecting fracruring fluid, acid pre- treatment, filling sand in the pad, controlling sand ratio, applying the techiniques of fracturing diaognose and flowing back fracturing fluid timely.