Abstract: This paper introduces the types, performances and application of macromolecular flocculating agent for produced water treatment in the world. Compared with cat-ionic and anionic macromolecular flocculating agent, zwit-terionic macromolecular flocculating agent has the advantages of wide adaptability range to pH value, good salt resistance, and strong capability of flocculation and precipitation and dehydration. Development trend of macromolecular flocculating agent for produced water treatment is presented.