Abstract: Based on the analysis of geology, rock mechanics and stress characteristics, the compressibility of Mouye-1 well was evaluated comprehensively. The results show that the favorable factors are high brittleness index, natural fracture development and large difference in ground stress. According to reservoir geology and engineering characteristics, the fracturing scheme was determined. The fracturing parameters are optimized and adjusted by numerical simulation. According to the fracturing pressure history fitting analysis and micro-seismic monitoring results, complex fractures of a certain scale are formed after pressure and the reconstruction range is relatively large. The daily output of 1,256 m~3 was obtained after gas test, and significant discovery of shale gas exploration in Henan province was obtained, which proves this block has a good prospect of exploration.