Abstract: Vertical wells are adopted for He3 gas reservoir in Daniudi gas field, which has the characteristics of high initial production, long stable production period, high cumulative production and good production effect. The recovery rate has reached 40%. In order to further improve the recovery rate of the gas reservoir, the study on production effect analysis and well pattern evaluation is carried out for He3 gas reservoir. The results show that the well pattern of He3 gas reservoir is generally reasonable and there is still a space for infilling adjustment in some parts. Among them, the compound channel bar has good connectivity, high cumulative yield and small infill space, while in the development area of middle and isolated channel bars, the well pattern has certain adjustment space and has the importantly tapping potential for the next step.