Abstract: Aiming at reservoir characteristics of Minghuazhen formation in Gangdong area,namely vertically and horizontally superimposed channels,big reservoir changes and thin single sand body thickness,the research on reservoir prediction has been carried out by comprehensively applying frequency-extended processing,reservoir calibration,seismic profile tracking,multi-attribute analysis and spectrum decomposition methods.The research successively described the development features of meandering rivers in Gangdong area and revealed multiple potential target zones.According to the results,the well location plan was deployed.After the implementation,the reservoir drilling encounter rate is high,which proves that this set of technology is effectively feasible and can improve the precision of reservoir prediction.